ea0081rc10.5 | Rapid Communications 10: Diabetes, Obesity, Metabolism and Nutrition 3 | ECE2022
Cantini Giulia
, Trabucco Martina
, Fei Laura
, Propato Arianna
, Guasti Daniele
, Quartararo Giovanni
, Maggi Mario
, Mannucci Edoardo
, Luconi Michaela
Obesity is associated with increased and dysfunctional white adipose tissue (WAT). Pharmacological approaches of obesity are still far from obtaining a stable weight loss. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been proposed as anti-obesity drugs due to their effects on weight loss. Furthermore, dual agonists engaging both GLP-1 and glucagon are currently under investigation for their marked effects on weight loss, although their mechanisms of action is stil...